Controlling Epileptiform Activity with Organic Electronic Ion Pumps

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Controlling epileptiform activity with organic electronic ion pumps.

In treating epilepsy, the ideal solution is to act at a seizure's onset, but only in the affected regions of the brain. Here, an organic electronic ion pump is demonstrated, which directly delivers on-demand pure molecules to specific brain regions. State-of-the-art organic devices and classical pharmacology are combined to control pathological activity in vitro, and the results are verified wi...

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Reading performance in children with rolandic epilepsy correlates with nocturnal epileptiform activity, but not with epileptiform activity while awake.

OBJECTIVE An association between language impairment and rolandic epilepsy is frequently reported. This impairment could be correlated with the amount of nocturnal epileptiform activity. METHODS We retrospectively analyzed 26 children with rolandic epilepsy and/or rolandic spikes. All had undergone a 24-hour EEG and neuropsychological assessment within 2 weeks. Reading performance (reading wo...

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ژورنال

عنوان ژورنال: Advanced Materials

سال: 2015

ISSN: 0935-9648

DOI: 10.1002/adma.201500482